Ed wrote on Nov 11^th, 2011 at 6:10pm:

Ihave always used the assumption that the powder that fills the case the most the better.

This may or may not be true, but shake a factory Remington or Winchester round (both are 180 grain soft points) and you'll hear loose powder which means that the cases are not filled completely.  In my humble opinion, I think it's better to work up a load that gives the best accuracy and (in the case of hunting) the most stopping power while keeping the pressures reletively low.  You might want to think about a 150-180 grain bullet with a higher rate of shock and expansion while keeping the volecity around 2000 to 2200.  Either way, I wish you the best of luck in your hunt!  Let us know what you wind up using...  Any data is good data for those who follow us to use!