Sierra's manual confirms that 4064 is just fine for .30/40 220-grain loads, giving similar velocity at acceptable pressure with lighter charges. Here's some of their data (from a 22" barrel) -

.308 220 gr. RN
Cartridge OAL: 3.000"

Vel. fps.     1800      1900      2000      2100            
IMR-4064      34.3      36.0      37.7      39.5      
IMR-4350      38.2      40.2      42.3      44.4

Standard primers should be OK for 4064. It's not hard to ignite.