That's what all the fellows at a Cast Bullet Association benchrest match that I attended were shooting a few years back.  It was working for them!  They all had heavy target rifles and small pieces of artillery, I shot my full length Krag with LER scope.   Most were shooting heavy 30 caliber bullets and said they had their loads at about the 2000fps level.  They were using cases of less capacity than the Krag, and favored Varget as their powder.