I've been using IMR-4350 for years... and never looked back (IMR is the former Dupont, which is the company that acquired the the original Laflin and Rand company, which produced the W.A. 30 Caliber powder originally used in Krag ammo).  All that said, I'm sure that H4350 would produce great results too.  (Hercules did acquire the patents for many of Laflin and Rand's powders, including Bullseye and Unique)

Now, I DID switch from IMR-4895 to H4895 for my 30-06 rounds in my Garand and 1903A3... and I DO believe the results are better!

One final note:  I do believe H4350 would be cleaner burning than IMR-4350, which is quite dirty.  H4895 is similarly cleaner than IMR-4895.