NO!!  Those BP substitutes have well-deserved reputations for rusting barrels & actions long after you thought you had cleaned them.  I learned that the hard & expensive way.  My fancy Hepburn doesn't shoot so good anymore.

Not only that, but the Krag cartridge case was designed for smokeless from Day 1.  Shooters have been having good results with cast bullets and smokeless powder in Krags for more than 120 years.  Lots of info in cast bullet loading manuals.  Stick with IMR powders, mainly 4198 and 3031.  The real secret is using good cast bullets, proper alloy & lube, going slow & keeping good records.  Keep velocity under 1500 for starters.

For safety sake, stay away from 5744.  That has wrecked a bunch of rifles chambered for bottle-necked cartridges.